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The Phase 2 data published in the New England Journal of Medicine by Jastreboff and colleagues in 2023 showed dose-dependent weight loss peaking at 24.2% of baseline body weight at 48 weeks on the 12 mg dose

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If you want to check the science yourself rather than take a clinics word for it, review the peer reviewed medical literature indexed in the National Institutes of Health PubMed Central library explaining why large peptide molecules resist passive absorption through intact skin without specialized delivery systems

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